Missouri cannabis testing requirements

Required tests

• Potency
• Pesticides
• Residual solvents
• Heavy metals
• Microbials
• Mycotoxins
• Water activity
• Moisture
• Foreign matter
• Homogeneity
• Vitamin E acetate

ISO/IEC 17025 accreditation

Required within a set period. 12 months. Testing labs must be accredited to ISO/IEC 17025 by an ILAC-recognized body within one year of department approval to operate, and may not test if they miss that deadline or lose accreditation (19 CSR 100-1.110(3)(B)).

Notes

• Testing rule: 19 CSR 100-1.110, part of the 19 CSR 100-1 rule set effective May 30, 2026.
• The testing lab collects the sample itself; the whole lot must be available and a licensee employee must watch.
• Microbials: STEC/pathogenic E. coli, Salmonella and Aspergillus (4 species) not detectable in 1 g. Mycotoxins: aflatoxins plus ochratoxin A fail above 20 µg/kg.
• Heavy metals: arsenic, cadmium, chromium, lead, mercury. Vitamin E acetate is on the chemical residue list for inhalables and concentrates only.
• Water activity: 0.65 aw max for flower, prerolls, hash and kief (flower and prerolls also 5-15% moisture); 0.85 aw max for solid infused products.
• Potency covers 8 cannabinoids; results from at least 3 samples may deviate no more than 15% from the lot mean (listed here as homogeneity).
• Terpene analysis is optional. Heavy-metal failures cannot be remediated; other failures can be reanalyzed, remediated or destroyed.
• Labs take part in annual ISO/IEC 17043 proficiency testing and state-directed inter-lab comparisons.