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South Dakota cannabis testing requirements

Verified 28 September 2026Medical only

South Dakota's Department of Health runs the medical cannabis program voters created in 2020; adult use is not legal. Every batch must pass testing at a registered cannabis testing facility before retail sale: THC potency, pesticides, microbials, mycotoxins, heavy metals and residual solvents. Labs must be working toward ISO/IEC 17025 before testing and be accredited within 32 months.

The rulesVerified 28 September 2026

What South Dakota asks of a testing lab

South Dakota cannabis testing facts
Medical programYes
Adult-use programNo
State-mandated testingRequired
Required tests6 test categories
ISO/IEC 17025Required within a set period
RegulatorSouth Dakota Department of Health, Medical Cannabis Program ↗
Last verified28 September 2026

Required tests

  • Potency
  • Pesticides
  • Residual solvents
  • Heavy metals
  • Microbials
  • Mycotoxins

ISO/IEC 17025 accreditation

Required within a set period. ARSD 44:90:06:01 (amended 4 August 2025): a lab must be working with an accreditation body before it accepts samples and must complete ISO/IEC 17025 accreditation within 32 months of registration, or its registration is revoked.

Notes

  • Rules: ARSD 44:90:06 (testing facilities) and 44:90:09 (sampling and testing); action levels in 44:90:05:10 and 44:90:07:03.
  • Potency: THC, plus CBD when labeled; THC may not vary more than 10% from the label.
  • Microbials: total aerobic bacteria, total yeast and mold, bile-tolerant gram-negative bacteria; STEC, Salmonella and Aspergillus (fumigatus, flavus, terreus, niger) under 1 CFU/g.
  • Mycotoxins: aflatoxins B1, B2, G1, G2 and ochratoxin A. Heavy metals: arsenic, cadmium, lead, mercury.
  • Pesticides: 13 listed analytes plus any prohibited synthetic pesticide. Residual solvents: separate action levels for inhalable and other products.
  • Water activity and moisture are not on the mandatory list.
  • Labs must register with the DEA (ARSD 44:90:06:01).
  • The department runs confirmation testing, with the South Dakota Public Health Laboratory; since 1 January 2024 it may test accredited labs less often if they pass proficiency testing.
  • Voters approved IM 26 (medical) in 2020 and rejected adult-use measures IM 27 (2022) and IM 29 (2024).

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